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Cocamidopropyl Dimethylamine Oxide: More Than a Fancy Name

Historical Development: The Rise of Surfactants in Everyday Life

Cocamidopropyl Dimethylamine Oxide didn’t make headlines overnight. Chemists started looking for safer, more versatile surfactants back in the mid-20th century, moving away from soap-based cleaners that dried out skin and couldn’t handle hard water. By the 1970s, research shifted to molecules based on coconut oil, because plant-based feedstocks carry fewer environmental downsides than older petroleum options and offer built-in mildness. The push for lower skin irritation in personal care drove big investments in developing these types of surfactants. Raw material availability, tightening regulations, and growth in mass-market skin and hair products gave the coconut-derived chemical family—including Cocoamidopropylamine Oxide—its commercial runway. As cosmetic and homecare brands expanded globally, formulators hunted for flexible, dependable ingredients that wouldn’t drive up costs or raise tougher import/export hurdles. That’s how a quirky-sounding molecule made its way from obscure patent applications to most bathroom shelves today.

Product Overview: A Surfactant With Versatility

This chemical looks like a clear-to-pale yellow liquid and solves plenty of solubility puzzles when making shampoos, body washes, face cleansers, and even some hard surface cleaners. Its amphoteric structure, meaning it can work as a mild detergent and boost foam without creating loads of skin irritation, sets it apart from old-school surfactants known for stripping oils. Not just a cleansers’ helper, it acts as a foam builder, viscosity booster, and stable partner for anionic agents like sodium laureth sulfate. Its coconut oil heritage puts formulators on friendlier ground for “natural origin” claims compared to options derived solely from petroleum. That’s a big deal in personal care and green household cleaning.

Physical & Chemical Properties

Cocamidopropyl Dimethylamine Oxide usually comes with a pH in the 6.0–8.5 zone, helping preserve product stability without a bunch of fiddling. Its surface tension falls into a range that supports stable foams, even in hard water or in the presence of oily residues, which explains its popularity for cleansing. The molecule’s moderate viscosity lines it up for easy pouring and blending, but it doesn’t go runny, so producers can fill bottles without a mess. The substance dissolves fully in water, resists breaking down in storage, and holds up through a variety of temperatures most bathroom or kitchen products face in transport and home use. Viscosity can spike if cool temperatures set in, but standard processing addresses that problem.

Technical Specifications & Labeling

Producers typically supply the product as an aqueous solution, often at 30% active concentration, labeled according to international standards like INCI (International Nomenclature of Cosmetic Ingredients) and linked to identifiers like CAS number 61792-31-2. Product sheets flag key benchmarks for purity, amine oxide content, free amine content, and residual amidoamine. For regulatory compliance, suppliers follow ISO and national guidelines on hazard labeling, shipping, and batch traceability. OTC and personal care goods present the ingredient under its INCI name, giving label readers an exact, consistent way to spot this surfactant. Most brands highlight its “coconut derived” or “plant-based” status for credibility with eco-savvy consumers, but the technical paperwork keeps close tabs on impurity control.

Preparation Method: Chemistry on a Practical Level

Manufacturing Cocamidopropyl Dimethylamine Oxide follows a two-step journey. It starts with fatty acids or methyl esters from coconut oil—those give the molecule its “coca” prefix. These are reacted with dimethylaminopropylamine to yield a tertiary amine. Next, controlled oxidation with hydrogen peroxide, or a similar oxidizer, converts the amine to an amine oxide. Several quality tests check for unreacted amines or byproducts, because even traces can bump up skin sensitivity. Producers run pH adjustment, filtration, and dilution before shipping, so companies formulating end products can rely on consistency. Manufacturing needs careful temperature and feedstock control to avoid residual contaminants and support claims around gentle use.

Chemical Reactions & Modifications

The amine oxide group brings key reactivity. The molecule stays gentle under normal conditions, but shows resilience to acids and alkali that wreck less robust surfactants, making it handy for a wide pH range. It pairs with ionic surfactants in multi-surfactant blends to raise foam, stabilize emulsions, or thicken formulations. The basic structure allows for tweaks: producers swap fatty acid chains for varying degrees of hydrophobicity, and alter the amine side group to target different solubility or foam properties depending on what the customer wants—to dial up oil removal or stretch out foam stability, for example. Cocamidopropylalka amine oxides stand out for their compatibility with cationic ingredients, allowing for dual-action cleaning or conditioning systems in single-step products.

Synonyms & Product Names

Across technical literature and commercial packaging, Cocamidopropyl Dimethylamine Oxide pops up with several aliases. Industry shorthand includes variants like Cocamidopropylamine Oxide or CAPDAO. Trade names change by producer, but many stick to INCI or CAS annotations. In detergent chemistry manuals, it gets referenced under “amine oxides” or fatty acid amine oxides, making it easier for researchers to find its backbone among competing options. Some suppliers label it under their proprietary blends, incorporating the oxide with other amphoteric or nonionic surfactants, but product codes almost always call out the main constituent. This sea of names can trip up formulators, but careful review of technical sheets ties the product to its key chemical features fast.

Safety & Operational Standards

Worker handling follows industry norms: Eye and skin protection ranks high, because raw and concentrated forms can irritate mucous membranes. In finished consumer goods at typical concentrations, reviews by agencies like CIR (Cosmetic Ingredient Review) and SCCS (EU Scientific Committee on Consumer Safety) point to low risk—provided the manufacturing process removes residual amines and unreacted starting material. Suppliers meet requirements under REACH, U.S. TSCA inventory, and the Globally Harmonized System for hazard communication. Waste handling instructions carry weight, since plant and downstream users want to minimize aquatic impact. Product sheets advise on accident protocols—eye flushing, ventilation, and skin washing routines. Any operator experience with chemical handling in consumer product manufacturing translates easily, but companies invest in training because product quality depends on reliable batch-to-batch controls all the way from raw to finished form.

Application Area: Not Just for Soap

Cocamidopropyl Dimethylamine Oxide’s impact stretches way past shampoo bottles. Its foam and mildness combine with cleaning power, which makes it a favorite in everything from dish soap to industrial degreasers. Companies running large-scale kitchens and food processing turn to amine oxides for grease-trapping, because the chemical doesn’t knock out skin or metal surfaces. Pet grooming lines build on its gentleness and dirt removal, letting owners clean sensitive skin types. Auto detailers rely on it for foaming car wash solutions that cut through road film without streaking or spotting paint jobs. Hospitals and clinics value its synergy with biocidal agents in surface disinfectants, because it supports broader spectrum activity. Its mild, non-strip cleaning profile serves both the hypoallergenic needs of sensitive users and the heavy-duty dirt removal demanded by mechanics. Now, green formulators highlight its “plant-derived” roots, using the molecule to transition products away from less biodegradable, petroleum-heavy blends, cementing its place in next-gen formulas fueled by consumer trust in safer, more eco-aligned solutions.

Research & Development: Chasing Better Performance

Laboratories keep pushing Cocamidopropyl Dimethylamine Oxide towards new frontiers. One big pursuit focuses on enhanced biodegradability and improving breakdown pathways in wastewater, as regions clamp down on persistent ingredients in effluent. Another track looks at optimizing the molecule’s ability to partner with other gentle surfactants to take cleaning strength up a notch without triggering skin reactions. Benchmarking trials line Cocamidopropyl Dimethylamine Oxide up against newer sugar-based surfactants to measure skin friendliness and foaming power directly in consumer use studies, not just the chemistry lab. R&D teams also engineer modifications—changing chain length, tweaking headgroup size—to deliver tailored characteristics for highly specialized cleaning or skincare needs. Patent filings keep climbing, documenting tweaks not just to the base molecule, but processing and purification steps that can lower cost and improve environment scores on lifecycle analyses. Collaboration between raw material providers, formulators, and even dermatologists keeps ingredient designers focused on real-world performance and safety, not just chemical theory. The future is built around direct user feedback as much as bench science.

Toxicity Research: Keeping Safety in Sharp Focus

Current toxicological data gives Cocamidopropyl Dimethylamine Oxide a low acute toxicity score when used at consumer product levels. Its eye and skin irritation profile depends more on leftover free amine or byproducts than the finished oxide itself, prompting close attention during manufacturing. Regulatory boards regularly review each new animal alternative test and patch test result to check for allergenic or sensitization potential. Companies leaning into green chemistry invest in studies measuring biodegradation rates, aquatic toxicity, and chronic exposure risk. Recent findings show that with proper process controls, the surfactant rinses off cleanly and doesn’t build up hazards for aquatic life. Reviews of accidental oral ingestion or inhalation in workplace scenarios point to low risk, provided standard safety gear and handling routines keep direct contact brief. Ongoing research into cumulative effects guides safety limit setting as consumer demand shifts and regulation evolves.

Future Prospects: Innovation Driven by Real-World Need

Growing pressure for sustainable chemistry keeps Cocamidopropyl Dimethylamine Oxide in the innovation spotlight. Producers chase renewable feedstocks and enzyme-driven synthesis, lowering environmental footprints and fossil fuel dependence. Formulators rework classic cleaning tools, shifting heavily toward ingredient lists featuring well-tested, low-toxicity surfactants like this one. As consumer awareness rises, brands publish traceability and safety validation data, with ingredient transparency ranked even higher than basic product claims. Product development shifts aim at building even milder versions, tuning the balance of hydrophobic and hydrophilic properties, and fitting high-efficacy cleaning into minimalist, eco-packed formulas. Emerging concerns about microplastics and persistent contaminants push the surfactant sector to lean on molecules that can prove their safety and break down fully in the environment. As more research clarifies how these ingredients behave over their whole lifecycle, Cocamidopropyl Dimethylamine Oxide stands out as a molecule balancing history, safety, and performance, showing how chemistry can meet both consumer needs and a shifting regulatory landscape.



What is Cocamidopropyl Dimethylamine Oxide used for?

What Is It, and Why Should Anybody Care?

Cocamidopropyl dimethylamine oxide doesn’t roll off the tongue. It pops up on ingredient labels in all sorts of products, mostly in the cleaning aisle or personal care section. Looking at the chemical’s name doesn’t help much, either. Yet, it serves a real purpose in the lives of people who want dishes washed, hair cleaned, or counters wiped down effectively.

How This Ingredient Fits into Cleaning and Personal Care

This compound works as a surfactant—think soap, but more versatile. Surfactants break up greasy messes and stubborn residue. Cocamidopropyl dimethylamine oxide stands out for its ability to produce thick foam and stabilize bubbles. Shampoos, body washes, dish detergents, and all-purpose cleaners gain a distinct sensory appeal from its presence. Consumers recognize products that lather well as more effective, even if that isn’t always the case.

As someone who handles dishwashing and laundry at home, foamy products just feel like they’re doing the job. So brands keep turning to versatile ingredients that help fulfill that expectation, and this one fits the bill. It releases dirt, rinses away clean, and doesn’t cling to skin or fabric once washed out.

Skin Safety and Ingredient Origins

Plenty of folks care about what they touch, especially if rashes or sensitivities run in the family. Cocamidopropyl dimethylamine oxide gets manufactured from fatty acids that begin in coconut or palm oil. Naturally-derived ingredients attract consumers searching for plant-based alternatives. This chemical isn’t all-natural, but it brings the gentleness of coconut through a chemistry process.

Regulators and dermatologists consider the ingredient safe for most. Regulatory bodies in Europe, the US, and other regions evaluate its safety through studies and risk assessments. Some people may experience mild irritation, especially in high concentrations or poorly mixed formulas. Personal care brands usually add it in modest amounts, enough to clean but not enough to trigger discomfort. Anyone with sensitive skin should still patch test new products before regular use—a habit that pays off in comfort.

Environmental Impact and Ongoing Questions

As more families worry about microplastics, water quality, and the bigger picture, these questions matter: Where does it go when the suds wash down the drain? Cocamidopropyl dimethylamine oxide breaks down more quickly than traditional surfactants derived from petroleum. According to the Environmental Working Group and similar organizations, it has a relatively low impact on aquatic life, provided it’s used as directed and doesn’t end up in huge, concentrated spills.

Some researchers and advocacy groups push for clearer labelling and more studies on byproducts that come out of manufacturing this chemical. Ingredient transparency keeps companies and shoppers honest, and I always make it a point to look for brands willing to explain where their ingredients come from and how they source them.

Choices and Demand Shape the Future

Walk down the aisle and the rows of shampoo and dish soap seem endless. People want to see words like “gentle,” “plant-based,” or “eco-friendly.” Ingredients like cocamidopropyl dimethylamine oxide bridge the gap between performance and peace of mind. They offer foaminess and gentle cleansing, with fewer drawbacks compared to harsher surfactants.

Tougher questions still need answers: How can we ensure raw materials don’t come from destructive farming? Will manufacturers keep moving toward cleaner, safer formulas for both people and the planet? My hope is that, as information flows more freely, choices grow in both number and quality. In the end, every ingredient matters—right down to those with the longest names on the list.

Is Cocamidopropyl Dimethylamine Oxide safe for skin and hair?

Looking Beyond the Label

Shampoo bottles and hand soaps often list tongue-twisters like Cocamidopropyl Dimethylamine Oxide in the ingredients. Coming across this surfactant in a personal care product sometimes triggers hesitation, and it makes sense—long names tend to set off alarm bells. I remember the first time I tried to pronounce this ingredient, searching online just to make sense of what I was actually putting on my scalp. Companies use it to help water and oil mix, which builds that familiar lather in so many cleansers.

Understanding the Ingredient

Cocamidopropyl Dimethylamine Oxide comes from coconut oil and amines. It acts as a foam booster and a mild cleanser in a lot of body washes, shampoos, and even facial cleansers. Based on public safety data from organizations like the Cosmetic Ingredient Review and research in peer-reviewed journals, this ingredient generally doesn’t cause problems for most people. The CIR Expert Panel reviewed similar amine oxides back in 2013 and found them safe for rinse-off use at typical concentrations. Most shampoos use less than 5%—often far lower.

What Does Science Say About Reactions?

I’ve heard all kinds of stories from people with sensitive skin or eczema who scan every ingredient. With any surfactant, the real risk is overuse or using a product that isn’t matched to your skin’s needs. For this surfactant, scientists haven’t flagged any recurring issues in people without an already irritated scalp. Most reports link irritation to either extremely high concentrations or poorly formulated products. Allergies to amine oxides like this one show up extremely rarely in testing, and usually after repeated contact, not from a single use.

Looking through the research, irritations tend to be more likely from residual impurities—traces left over in the manufacturing process—than from the main molecule. Choosing products with reputable brand backing helps because stricter quality control leaves fewer contaminants behind. My own dermatologist pointed out that patch testing offers a way to be sure when transitioning to a new formula, especially for anyone with sensitive skin or an allergy history.

Environmental Impact and Safety

This ingredient breaks down fairly well in the environment compared to older cleansing agents. Surveys of wastewater treatment show most amine oxides won’t persist and cause trouble for wildlife at the levels found in the typical bottle of soap or shampoo. Still, choosing products with biodegradable surfactants adds confidence that what rinses down the drain doesn’t sit in rivers or oceans for years.

How to Reduce Risk and Stay Comfortable

Reading ingredient lists stays important for anyone who’s had issues with surfactants, fragrance, or preservatives in the past. I switch brands every so often and stick to products with shorter ingredient lists if my scalp starts to feel dry. For anyone concerned about possible irritation, a quick patch test behind the ear does more than guesswork. Sensitive skin sometimes needs a break from anything with strong cleansing action. That doesn’t mean you have to give up on suds—just pick formulas intended for your hair or skin type and rinse well. If redness or itching shows up, switching to a simple, gentle alternative often brings relief.

Is Cocamidopropyl Dimethylamine Oxide natural or synthetic?

Where Cocamidopropyl Dimethylamine Oxide Comes From

Shoppers scan ingredient labels and weigh personal care choices on a growing scale these days. Words like “natural” and “synthetic” travel far in marketing, but for cocamidopropyl dimethylamine oxide, clarity proves slippery. Cocamidopropyl dimethylamine oxide doesn’t sprout up from a leafy field or flow from springs. It starts with coconut oil, but a long process in a chemical plant turns it into an ingredient you find in shampoos and soaps. Turning raw coconut oil into surfactants like this one involves reactions with petroleum-derived chemicals such as dimethylamine and hydrogen peroxide—these are not found on trees.

How the Ingredient Gets Made

Having spent many years testing formulations in small labs, I’ve seen the journey from coconut oil to an ingredient list on a shampoo bottle. First, manufacturers strip and refine coconut oil to extract fatty acids. These acids then react with dimethylamine, a synthetic chemical. After this, they subject the blend to oxygen or hydrogen peroxide to create the finished product. Though coconut oil starts the process, the end compound doesn’t resemble anything you’d crush from a nut at home.

Inside a bottle, cocamidopropyl dimethylamine oxide helps shampoo foam and spread by reducing surface tension. This surfactant works well because its synthetic transformation brings reliability: clear appearance, consistent scent, and dependable cleansing. Synthetic ingredients like these survive longer on shelves and blend evenly into products.

Is It Still “Natural”?

Plenty of companies advertise ingredients as “derived from coconut” or “plant-based,” which sounds comforting. Unfortunately, this label distracts from the serious lab work involved. Whether it starts from something from a plant, heavy chemical alteration strips away most of the original material’s properties. Regulatory agencies like the U.S. Food and Drug Administration don’t have a legal definition for “natural.” So a product can be labeled natural if even a tiny part of its process once involved a plant, no matter how dramatically it was changed in the lab later.

As a chemist who cares about honesty, I see why this frustrates consumers striving for clean choices. Marketing spins “coconut-derived” as safe and gentle, but the real story is more complex. Between 2002 and 2004, cocamidopropyl-based surfactants landed on allergen “watch lists” after reports of contact dermatitis increased, mainly because leftover reactants like amidoamine can irritate skin. Even though refinements have improved safety, no one wants confusion here.

Ways Forward for Transparency and Trust

If labels reflected the real production story, shoppers would have a better handle on what lands on their skin and in their homes. A clear system for defining “natural” and “synthetic” could help everyone navigate crowded shelves. Regulators and industry voices can work together—creating a glossary that forces specific wording and a limit to what counts as “plant-derived.” A straightforward, easy-to-understand ingredient disclosure in plain language can go a long way. In my experience with customers, this honesty reduces confusion and supports healthier decisions.

Until then, consumers looking to avoid synthetic surfactants will need to look past the big plant images and scan deeper into the ingredient decks. Reliable resources, like the Environmental Working Group’s Skin Deep database, can help by providing context around science-heavy names.

Final Thought

Cocamidopropyl dimethylamine oxide always traces important chemistry in its DNA, with a clear leap from coconut to lab. The ingredient may start natural, but it wears a synthetic badge by the time it foams up in your shower.

Can Cocamidopropyl Dimethylamine Oxide cause allergies or irritation?

What People Often Overlook About Everyday Ingredients

You can find Cocamidopropyl Dimethylamine Oxide in a long line of shampoos, hand soaps, and even household cleaners. It shows up because it boosts foam and helps surfactants work better together. Plenty of brands rely on it to deliver that squeaky-clean feeling or billowy bubbles that seem to give cleaning products an edge. Most people never read the long chemical name on the back of a bottle, much less think twice about what it does to their skin.

Experiences Speak Louder Than Labels

Many friends and family have shared that they struggle with dry, itchy skin after switching to a new soap or shower gel. Some blame the weather, hard water, or just say they have "sensitive skin." It's not always easy to spot which ingredient causes issues, since irritation doesn't flare up for every person every time. Dermatologists see reactions ranging from mild redness to full-on rashes. Skin complaints crop up more among people who use products with a host of synthetic surfactants, including Cocamidopropyl Dimethylamine Oxide.

The Facts Back Up Our Experience

Scientists have spent years tracking the allergic and irritation potential of modern personal care ingredients. Cocamidopropyl Dimethylamine Oxide, like its relative Cocamidopropyl Betaine, can disrupt the outer layers of the skin. Some people develop contact dermatitis, which looks like red, inflamed patches or tiny bumps. Peer-reviewed research points out that anyone with a history of skin allergies or eczema faces a greater risk from surfactants. In a world where more children and adults face sensitive skin, these reactions deserve closer attention.

Health agencies have acknowledged that this compound isn't risk-free. Dermatology organizations continue to list Cocamidopropyl derivatives among substances that may spark allergic reactions. This is especially true if a product sits on skin for a while, such as during a long shampoo or soak in the tub.

Why Transparency Matters in Everyday Choices

Growing up, most people never questioned what their soaps contained. The world now has more access to information — and more stories about people who discover they react badly to a product that worked fine for years. This shift in awareness helps families, especially those with small kids or a family history of allergies, stay cautious and look for better alternatives. It gives people a chance to make informed decisions and advocate for safer formulations.

Seeking Safer Solutions and Personal Ownership

Many brands have begun listing their ingredients more clearly on packaging and company websites. This transparency means that someone who starts noticing irritation or unexplained breakouts can trace the issue more quickly. Patch testing helps people find out if a product will cause problems before using it all over their skin. If a reaction happens, switching to less complex formulas, or trying products made for sensitive skin, usually brings relief.

Dermatologists recommend sticking to simple cleansers without unnecessary surfactants, especially for infants or those with a record of skin allergies. If irritation happens often, it's a good idea to seek professional advice so the right culprit gets identified. Reading up on what goes into our household goods puts power back in the hands of consumers. We can all benefit from taking a closer look before lathering up, so that daily routines bring comfort — not discomfort.

Is Cocamidopropyl Dimethylamine Oxide environmentally friendly or biodegradable?

What Is Cocamidopropyl Dimethylamine Oxide?

Many folks who read labels closely have probably noticed Cocamidopropyl Dimethylamine Oxide in their dish soap, shampoo, or bathroom cleaner. This chemical acts as a surfactant, helping water to mix better with oil and grime, which lets products get things squeaky clean. People have started worrying about the environmental track record of these cleaning helpers, especially as the conversation about waterway health grows louder.

How Does It Break Down?

This ingredient has a long, complicated name but sits at the core of the formulas in both home and commercial products. When flushed down the drain, Cocamidopropyl Dimethylamine Oxide doesn’t sit unchanged forever. Research from sources such as the OECD (Organisation for Economic Co-operation and Development) points out that many amine oxides, including Cocamidopropyl Dimethylamine Oxide, show pretty strong levels of biodegradability under aerobic conditions. These chemicals rely on bacteria in wastewater treatment plants to do much of the heavy lifting. Tests suggest that over 60% of this compound breaks down within 28 days when plenty of oxygen is present, and the right bacterial colonies are on hand. That number sticks close to international standards for what counts as “readily biodegradable.”

Does That Mean It’s Environmentally Friendly?

Calling anything poured down the drain “environmentally friendly” always involves some trade-offs. Even though Cocamidopropyl Dimethylamine Oxide usually breaks down fairly quickly, some things can get in the way. Not all water treatment facilities operate at maximum efficiency, and some chemicals might sneak through untreated. Runoff from homes in areas without modern wastewater treatment can send these compounds straight into streams or soil.

Scientists have looked at the effect on aquatic life. In concentrated doses, this surfactant can cause trouble for fish and smaller critters, messing with their ability to take in oxygen or irritating their bodies. Most products only use small amounts, and those levels dilute pretty fast in wastewater. Dilution isn’t the best strategy, though. Since people use more cleaning products every year, that can lead to small but steady buildup by the time water reaches rivers and lakes.

Making Safer Choices

People don’t need to throw away everything in their cleaning cupboard, but paying attention to product labels goes a long way. Choosing detergents and soaps labeled as “readily biodegradable” or “eco-certified” signals companies to keep focusing on lower-impact ingredients. Supporting stricter wastewater rules helps even more, since well-run municipal plants can filter out more of these chemicals before water flows back into the environment. Some brands use plant-based surfactants that break down even faster or leave less residue behind, though those still need to prove their performance over time.

Room for Change

Things always get better when companies listen to feedback. The cleaning supply industry can keep pumping out reports and investing in greener chemistry instead of sticking to older formulas. Product safety databases published by watchdog organizations and research groups can help shoppers double-check the biodegradability or ecotoxicity of their favorite brands. After seeing what works in other countries, agencies can bump up the standards at home for both chemical testing and wastewater cleanup.

Personal Experience

Some years back, trying to juggle cleaning up after toddlers and taking care of the garden raised questions at home about what ran down the drains. We switched to products listing full ingredient breakdowns and noticed fewer bubbles sticking around in the runoff water. From that point, learning which brands backed up their green claims with real data made it easier to feel confident every time a spill or sticky mess hit the floor.

Supporting Sustainability

Conversations about Cocamidopropyl Dimethylamine Oxide show that everyday choices shape bigger environmental outcomes. Asking questions and demanding transparency encourages manufacturers and local governments to step up. In the end, small steps—swapping out a single product or voting for better infrastructure—move the needle toward healthier rivers and communities.

Cocamidopropyl Dimethylamine Oxide