Product Name: Cocamidopropyl Dimethylamine Oxide
Synonyms: C12-14 Alkyl Amidopropyl Dimethylamine Oxide, Amine Oxide
Recommended Use: Surfactant for detergent and personal care applications
Manufacturer Information: [Full manufacturer company name, address, contact number]
Emergency Contact: [Emergency telephone number specific to region or company]
CAS Number: 68155-09-9
EC Number: 269-919-4
GHS Classification: Eye irritation Category 2, Skin irritation Category 2, Aquatic toxicity Category 3
Label Elements: Exclamation mark symbol, Warning signal word
Hazard Statements: Causes skin irritation. Causes serious eye irritation. Harmful to aquatic life.
Precautionary Statements: Avoid contact with eyes and skin. Wear suitable gloves and eye protection. Wash thoroughly after handling.
Other Hazards: No known significant immediate effects other than the above. Not classified as PBT or vPvB by current criteria.
Cocamidopropyl Dimethylamine Oxide: 27–33%
Water: 65–70%
Other Impurities: ≤2% (including minor residual amides, free amine, and salts)
Chemical Family: Amine oxide surfactant
Molecular Formula: Variable (RCONH(CH2)3N(CH3)2O), R = C12-14 alkyl chain
Inhalation: Remove to fresh air. Seek medical attention if symptoms persist.
Skin Contact: Rinse thoroughly with water. Remove contaminated clothing. If irritation occurs, consult a doctor.
Eye Contact: Rinse immediately with water for at least 15 minutes. Seek prompt medical attention.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Seek medical help.
Most Important Symptoms: Irritation, redness, discomfort in eyes and skin.
Immediate Medical Attention/Special Treatment: Symptomatic support recommended.
Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide.
Hazards from Combustion: May form carbon monoxide, carbon dioxide, nitrogen oxides under fire conditions.
Protective Equipment: Firefighters wear self-contained breathing apparatus and protective suit.
Specific Methods: Avoid run-off to water systems. Keep containers cool with water spray if possible.
Flammability: Not considered highly flammable but may support combustion.
Explosion Limits: Not applicable or not known.
Personal Precautions: Wear protective gloves, clothing, and eye protection. Evacuate area in event of major spill.
Environmental Precautions: Prevent release into waterways, drains, or soil. Notify authorities if significant spill reaches environment.
Containment/Clean-up: Absorb spillage with inert material such as sand or earth. Place residue in appropriate waste container. Wash spill site with water, ensuring clean-up residues are contained.
Ventilation: Provide adequate ventilation in area of release.
Disposal: Contaminated absorbent to be handled as described under Disposal Considerations.
Safe Handling: Use in well-ventilated areas. Avoid contact with eyes and skin. Do not eat, drink, or smoke while handling.
Hygiene Recommendations: Wash hands before breaks and after handling.
Storage Conditions: Store in a cool, dry, well-ventilated area. Keep container tightly closed.
Incompatibles: Avoid contact with strong oxidizers, acids.
Specific End Uses: Use only as recommended for surfactant and detergent manufacturing.
Packaging Materials: Store in plastic or steel drums compatible with organic surfactants.
Storage Temperature: Avoid storage below 0°C or above 40°C for product integrity.
Occupational Exposure Limits: No specific value established. Use general controls appropriate for chemical handling.
Engineering Controls: Provide local exhaust or general room ventilation.
Personal Protective Equipment:
— Eyes: Chemical goggles or face shield
— Hands: Impervious gloves such as nitrile rubber
— Skin: Apron or lab coat to prevent skin contact
— Respiratory: Not generally required, but use mask in case of mist or vapor formation
Environmental Controls: Prevent spillages, minimize fire risk, collect discharged material.
Other Protective Measures: Emergency eye wash stations should be available near handling areas.
Appearance: Clear to pale yellow liquid
Odor: Mild, amine-like
Odor Threshold: Not available
pH (10% solution): 6.0–9.0
Melting/Freezing Point: Below 0°C
Boiling Point/Range: Greater than 100°C
Flash Point: Not applicable (water-based)
Evaporation Rate: Similar to water
Flammability: Product is not highly flammable
Vapor Pressure: Low; comparable to water
Vapor Density: Not established
Relative Density: 1.02–1.04 (water = 1)
Solubility: Soluble in water
Partition Coefficient: log Kow not established for complex mixture
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not available
Viscosity: 100–500 cP at 25°C
Chemical Stability: Stable under recommended storage and use conditions.
Reactivity: Not reactive under normal storage and handling.
Hazardous Reactions: May react with strong oxidizers.
Conditions to Avoid: Prolonged heat, freezing, direct sunlight.
Materials to Avoid: Strong acids, oxidizing agents.
Decomposition Products: Oxides of carbon and nitrogen, amines.
Polymerization: No hazardous polymerization expected.
Likely Routes of Exposure: Skin and eye contact, accidental ingestion.
Acute Toxicity: Oral LD50 (rat) >2000 mg/kg (based on similar amine oxides)
Skin Corrosion/Irritation: May cause moderate skin irritation in susceptible individuals.
Eye Damage/Irritation: Severe eye irritant based on animal data.
Inhalation Risk: Low at ambient temperatures, but aerosols can irritate mucosa.
Sensitization: No data suggesting skin sensitization.
Chronic Effects: Prolonged repeated contact may cause dermatitis.
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No evidence from available data.
Medical Conditions Aggravated: Individuals with skin disorders may be more susceptible.
Aquatic Toxicity: Harmful in larger quantities to aquatic organisms. LC50 (fish, 96h): 1–10 mg/L (range typical for amine oxides).
Persistence and Degradability: Readily biodegradable under aerobic conditions (>60% in 28 days OECD 301 test).
Bioaccumulation Potential: Low; does not persist in biological tissues.
Mobility in Soil: High mobility; disperses rapidly in water.
Other Adverse Effects: Not classified as PBT or vPvB.
Ecotoxicity Note: Avoid uncontrolled discharge into environment to protect aquatic life.
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations.
Disposal of Product: Small amounts may be flushed to sewer with plenty of water where permitted, larger quantities to be disposed of by licensed waste handler.
Contaminated Packaging: Rinse empty containers before recycling or disposal.
Special Precautions: Prevent material from entering surface water or groundwater.
Classification for Disposal: Generally classified as non-hazardous but consult regional authority for restrictions.
UN Number: Not regulated for road, air, or sea transport in most regions.
Proper Shipping Name: Not defined as hazardous under standard transport rules.
Transport Hazard Class: Not applicable.
Packing Group: Not applicable.
Environmental Hazards: Not a marine pollutant.
Special Precautions for User: Ensure containers are securely closed and upright.
Bulk Transport: Compliant with MARPOL and IBC criteria for bulk chemicals.
Transport Remarks: Standard delivery vehicles; avoid temperature extremes.
EU Regulation: Listed on EINECS/ELINCS, classified under CLP.
US Regulation: Appears on TSCA Inventory.
Canada: Listed on DSL.
Australia: Listed on AICS.
Labeling: Irritant, may require environmental hazard label in high concentrations.
Occupational Regulations: Follow workplace safety acts for chemical handling.
Restrictions: Not subject to major use restrictions but use as recommended.
Chemical Safety Assessment: Not required for non-hazardous mixtures but available for main component.
Statutory Instruments: Follow national chemical safety regulations for worker and consumer protection.
