Product Name: Dioctadecyldimethylammonium Bromide
Synonyms: DDAB, Dimethyldioctadecylammonium bromide
CAS Number: 3282-73-3
Recommended Uses: Laboratory reagent, antimicrobial agent, lipid bilayer research
Supplier Contact: Emergency phone number, manufacturer/distributor address, technical information
Classification: Acute Toxicity (Oral - Category 4), Skin Irritation (Category 2), Serious Eye Damage (Category 1), Aquatic Acute (Category 1), Aquatic Chronic (Category 1)
Signal Word: Danger
Hazard Statements: Harmful if swallowed. Causes skin irritation. Causes serious eye damage. Very toxic to aquatic life with long lasting effects.
Pictograms: Exclamation mark, Corrosive, Environment
Precautionary Statements: Wear protective gloves, eye protection, face protection. Avoid release to environment. Wash thoroughly after handling.
Chemical Name: Dioctadecyldimethylammonium bromide
CAS Number: 3282-73-3
Concentration: >98% (by weight)
Impurities: Trace synthesis residues, not expected to contribute to hazard classification
General Advice: Seek immediate medical attention if symptoms appear. Provide detailed information on exposure.
Inhalation: Move affected individual to fresh air. If breathing difficulties persist, seek a physician.
Ingestion: Rinse mouth with water. Do not induce vomiting. Consult a doctor or Poison Center straight away.
Skin Contact: Remove contaminated clothing. Wash exposed area with soap and water for at least 15 minutes.
Eye Contact: Rinse with plenty of water for at least 15 minutes, lifting eyelids occasionally.
Most Important Symptoms: Skin or eye irritation, abdominal pain, nausea, headache if ingested or inhaled.
Notes for Physician: Treat symptoms. No antidote known. Monitor vital signs.
Suitable Extinguishing Media: Water spray, carbon dioxide, dry powder, or foam.
Unsuitable Media: Direct water jet may spread fire.
Specific Hazards: May decompose under fire to release toxic fumes, including bromine-containing compounds, nitrogen oxides, and carbon monoxide.
Protective Equipment: Self-contained breathing apparatus, full turnout gear.
Advice for Firefighters: Control run-off water to prevent environmental contamination. Stay upwind.
Personal Precautions: Avoid breathing dust. Keep unprotected individuals away from spill.
Protective Equipment: Chemical-resistant gloves, eye/face protection, disposable coveralls, boots.
Environmental Precautions: Prevent spill from entering waterways, drains, and soil.
Clean-up Methods: Sweep up with care, avoiding dust formation. Collect in a suitable, labeled container. Dispose according to regulations.
Disposal of Contaminated Material: Use chemical waste containers. Wash area thoroughly with water.
Precautions for Safe Handling: Avoid skin and eye contact. Avoid dust generation. Use within chemical fume hood if possible.
Incompatible Materials: Strong oxidizers, strong acids.
Storage Conditions: Keep tightly sealed in original container. Store in a cool, dry location, away from food and incompatible materials.
Special Requirements: Area should be well-ventilated, lockable if possible.
Engineering Controls: Use exhaust ventilation, fume hood, eyewash stations, safety showers.
Control Parameters: No occupational exposure limits established. Follow general dust and chemical exposure guidelines.
Personal Protective Equipment: Splash goggles, gloves (nitrile or neoprene), lab coat, respiratory protection for inadequate ventilation.
Hygiene Practices: Do not eat, drink, or smoke during use. Wash hands after handling.
Appearance: White to off-white crystalline powder
Odor: Slight, characteristic
Odor Threshold: Not established
pH (1% solution): 6.0–8.0
Melting Point: 40–44°C
Boiling Point: Not established; decomposes
Flash Point: Not flammable
Evaporation Rate: Not applicable
Flammability: Not readily combustible
Vapor Pressure: Negligible
Vapor Density: Not applicable
Solubility: Soluble in water, soluble in alcohols
Partition Coefficient (log Kow): >6.0 (estimated)
Auto-ignition Temperature: Not determined
Decomposition Temperature: >150°C
Viscosity: Not applicable
Chemical Stability: Stable under recommended conditions.
Hazardous Reactions: None expected under normal use.
Conditions to Avoid: High humidity, open flames, heat, incompatible materials.
Incompatible Materials: Strong oxidizers, strong acids.
Hazardous Decomposition Products: Bromine compounds, nitrogen oxides, carbon oxides.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.
Acute Effects: Harmful if swallowed, causes skin and eye irritation, may cause gastrointestinal distress.
Chronic Effects: Data lacking on long-term effects in humans.
LD50 (oral, rat): 740 mg/kg
Skin Irritation: Moderate to severe, based on animal studies.
Eye Irritation: Severe, risk of ocular damage.
Sensitization: Not classified; limited data.
Other Information: Not listed as a carcinogen by IARC, NTP, OSHA.
Aquatic Toxicity: Highly toxic to aquatic organisms, very long-lasting effects.
Persistence and Degradability: Not readily biodegradable. Persists in environment.
Bioaccumulative Potential: High, due to hydrophobicity.
Mobility in Soil: Low mobility, adsorbs strongly to soils and sediments.
Other Adverse Effects: Strong surfactant properties disrupt cell membranes in aquatic organisms.
Waste Disposal Methods: Dispose as hazardous chemical waste, following local, regional, national, and international regulations.
Contaminated Packaging: Dispose as hazardous waste, avoid reuse.
Precautions: Prevent contamination of surface and groundwater. Seek advice from waste disposal authority.
UN Number: 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains Dioctadecyldimethylammonium bromide)
Class: 9 (Miscellaneous dangerous substances)
Packing Group: III
Marine Pollutant: Yes
Special Precautions: Keep away from foodstuffs, animal feed, and incompatible materials. Notify carrier in advance.
TSCA Status: Listed
REACH Status: Registered/Pre-registered
SARA 313: Not listed
California Prop 65: Not listed
Other Regulations: Confirm all applicable workplace or chemical safety laws local to user’s jurisdiction.
Workplace Labeling: Required for containers used in laboratories or industrial settings.
