Product Name: Dodecyl Primary Amine
Chemical Formula: C12H25NH2
Synonyms: Laurylamine, 1-Dodecanamine
CAS Number: 124-22-1
Recommended Use: Surfactant, flotation agent, chemical intermediate
Manufacturer/Supplier Information: Available through chemical suppliers, distributed worldwide by specialty chemical providers
Emergency Contact: Refer to regional poison control center or emergency number listed by supplier
Classification: Skin corrosion/irritation (Category 1B), Acute toxicity (Inhalation, Category 3), Aquatic Acute Hazard (Category 1)
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage. Harmful if inhaled. Very toxic to aquatic life.
Precautionary Statements: Avoid breathing dust or vapor. Wear protective gloves, eye protection, and face protection. Keep container tightly closed. Do not release into the environment.
Chemical Identity: Dodecylamine
Common Name: Laurylamine
Purity: Typically above 95%
Impurities: May contain minor homologous amines or residual starting materials, below reportable thresholds
Inhalation: Move person to fresh air. Call a physician if symptoms like coughing, difficulty breathing, or throat irritation develop.
Skin Contact: Immediately wash with soap and plenty of water for at least 15 minutes. Remove contaminated clothing.
Eye Contact: Flush with large amounts of water for at least 20 minutes, lifting upper and lower lids. Seek medical attention promptly.
Ingestion: Rinse mouth. Do not induce vomiting. Seek immediate medical care. Do not give anything by mouth if the person is unconscious.
Suitable Extinguishing Media: Use alcohol-resistant foam, carbon dioxide, extinguishing powder, or water spray.
Unsuitable Media: Direct jets of water can spread burning liquid.
Specific Hazards: Produces toxic vapors including nitrogen oxides, amines, and carbon oxides during combustion. Vapors heavier than air.
Protective Equipment: Wear self-contained breathing apparatus, full protective gear.
Fire-Fighting Procedures: Remove containers from area if safe, use spray to cool exposed surfaces.
Personal Precautions: Evacuate area, avoid inhalation and contact with skin or eyes. Use suitable PPE including chemical-resistant gloves and protective goggles.
Environmental Precautions: Prevent release into sewers, surface, or ground water. Alert local environmental authorities if product enters waterways.
Spill Cleanup Methods: Contain spillage using non-combustible absorbent materials (sand, earth, or inert materials). Transfer waste to labeled, sealed containers for proper disposal. Ventilate area.
Handling: Use only in well-ventilated areas. Do not breathe dust, vapor, or mist. Avoid spills and contact with skin or eyes.
Hygiene Measures: Wash hands and exposed skin thoroughly after handling. Remove and wash contaminated clothing before reuse.
Storage Conditions: Store in tightly closed containers, away from food and incompatible materials such as acids, strong oxidizers, and bases. Keep container in a cool, well-ventilated location, protected from moisture.
Control Parameters: No established occupational exposure limits in many countries. Use workplace monitoring methods if available.
Engineering Controls: Provide local exhaust ventilation and eyewash stations in work areas.
Personal Protective Equipment: Use chemical-resistant gloves (nitrile or butyl rubber), safety goggles, and laboratory coats or coveralls. Respiratory protection with approved cartridge if airborne concentrations exceed comfort or known limits.
Appearance: Colorless to pale yellow liquid or solid (dependent on temperature)
Odor: Fishy, ammoniacal
Melting Point: 27–29 °C
Boiling Point: 259–261 °C
Flash Point: 121 °C (open cup)
Solubility: Insoluble in water, soluble in organic solvents (alcohol, ether)
Density: 0.79–0.81 g/cm³
Vapor Pressure: Low at room temperature
pH: Basic in aqueous solution
Partition Coefficient (log Kow): approximately 5.2
Chemical Stability: Stable under recommended storage conditions.
Potential Reactions: Reacts vigorously with acids, oxidizers, and acid chlorides. Can form hazardous nitrosamines when reacting with nitrites.
Hazardous Decomposition: Ammonia, hydrocarbons, nitrogen oxides, toxic organic vapors.
Acute Toxicity: Oral LD50 (rat): 930 mg/kg. Inhalation may cause respiratory irritation and chest discomfort. Skin and eye contact result in burns or severe irritation.
Chronic Effects: Prolonged exposure may cause dermatitis, respiratory sensitization.
Carcinogenicity: Not identified as a carcinogen by IARC, NTP, OSHA.
Mutagenicity/Teratogenicity: Data not sufficient, not expected at low levels based on analogues.
Target Organs: Eyes, skin, respiratory tract.
Aquatic Toxicity: Highly toxic to fish and aquatic invertebrates (EC50 < 1 mg/L).
Persistence: Not readily biodegradable; risk of accumulation in sediments.
Bioaccumulation Potential: High, due to strong hydrophobic character (log Kow > 5).
Soil Mobility: Low, binds to soil particles. Risk for ground water contamination exists with large spills.
Environmental Fate: Can form persistent residues; ecosystems near industrial releases may be at risk.
Waste Treatment Methods: Dispose as hazardous waste through licensed chemical disposal contractors. Incineration in approved facilities recommended.
Contaminated Containers: Rinse with suitable solvent, then offer for recycling or regulated disposal.
Local Regulations: Disposal must comply with local, regional, national, and international regulations. Do not discharge to drains or the environment.
UN Number: 2735
UN Proper Shipping Name: Amines, liquid, corrosive, n.o.s. (contains Dodecylamine)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: II
Labels Required: Corrosive, Environmentally Hazardous Substance (if shipped with large quantities)
Special Transport Precautions: Prevent spillage during transport. Check for compatibility with vehicle/container.
Global Inventory Status: Listed on TSCA (USA), EINECS (EU), DSL (Canada), ENCS (Japan).
OSHA Hazard Communication: Classified as hazardous. Safety training and labeling required.
ECHA Registration: REACH Registered in the EU.
SARA 313: Not subject to reporting.
WHMIS Classification (Canada): Class E (Corrosive Material)
California Prop 65: Not listed.
