Product name: Tributylmethylammonium Bromide
Chemical formula: C13H30BrN
CAS number: 3709-29-1
Synonyms: Methyltributylammonium bromide, MeTBA Br
Manufacturer: Contact local supplier or chemical distributor
Recommended use: Phase transfer catalyst, laboratory research
Restrictions on use: Not for food, drug, or household use
Emergency contact: Refer to institution safety office or CHEMTREC
GHS classification: Irritant to skin and eyes, harmful if swallowed
Signal word: Warning
Hazard statements: May cause skin irritation, serious eye irritation, and respiratory discomfort. Harmful if ingested.
Precautionary statements: Avoid inhalation of dust, avoid contact with skin and eyes, wear suitable protective equipment. Wash hands thoroughly after handling.
Hazard pictograms: Exclamation mark (GHS07)
Routes of exposure: Inhalation, ingestion, skin and eye contact.
Chemical identity: Tributylmethylammonium Bromide
CAS number: 3709-29-1
EC number: 223-059-4
Purity: ≥98% (typical for laboratory grade)
Impurities contributing to hazard: None reported at commonly available purity.
General advice: Move affected person away from source of exposure and to fresh air. Remove contaminated clothing.
Inhalation: Bring person to fresh air. Seek medical attention if symptoms such as coughing or difficulty breathing persist.
Skin contact: Wash thoroughly with soap and water. Remove contaminated clothing. Get medical advice if irritation remains.
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses if present, keep rinsing. Seek medical help if irritation continues.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting. Consult a physician immediately. Never give anything by mouth to an unconscious person.
Notes for medical personnel: Treat symptoms, provide supportive therapy as required.
Suitable extinguishing media: Use water spray, dry chemical, alcohol-resistant foam, or carbon dioxide.
Unsuitable extinguishing media: Avoid high-pressure water jets.
Specific hazards arising from the substance: Thermal decomposition may release toxic fumes of carbon oxides, nitrogen oxides, hydrogen bromide.
Advice for firefighters: Wear self-contained breathing apparatus and protective suit. Avoid inhaling gases or smoke.
Special protective actions: Remain upwind and avoid smoke exposure. Cool exposed containers with water spray to prevent rupture.
Personal precautions: Ventilate area. Avoid dust formation and direct contact with the material. Wear protective gloves, goggles, and mask.
Environmental precautions: Prevent release into sewers, soil, and water systems. Contain spill with inert absorbent materials.
Methods for cleaning up: Sweep up and place in suitable, sealed containers for disposal. Decontaminate area with water and detergent. Dispose of collected material in accordance with local regulations.
Additional guidance: Clean minor residues promptly to reduce slipping risk.
Safe handling advice: Use only in well-ventilated areas. Wear standard laboratory personal protective equipment. Avoid contact with eyes, skin, and clothing. Do not breathe dust.
Storage conditions: Keep in a tightly closed container, stored in a cool, dry, and well-ventilated place. Protect from light, heat, and moisture.
Incompatible materials: Strong oxidizers, acids, and bases. Materials capable of releasing bromine.
Other precautions: Keep away from food, beverages, and animal feed areas.
Engineering controls: Use local exhaust or general laboratory ventilation. Install eyewash stations and safety showers nearby.
Respiratory protection: Use NIOSH-approved respirator if airborne dust levels exceed occupational limits.
Hand protection: Wear chemical-resistant gloves (nitrile or PVC recommended).
Eye protection: Safety goggles or face shield.
Skin and body protection: Lab coat, apron, or protective clothing to prevent skin contact.
Hygiene measures: Wash hands after handling, remove contaminated clothing and wash before reuse. Do not eat or drink while handling chemicals.
Appearance: White or off-white crystalline powder
Odor: Odorless
Molecular weight: 292.29 g/mol
Melting point: 285–290°C
Boiling point: Decomposes before boiling
Solubility: Soluble in water, alcohols, and polar organic solvents
pH (1% solution): Approximate 7
Vapor pressure: Not applicable (solid at ambient temperature)
Density: ~1.09 g/cm3 (solid)
Flash point: Not flammable under typical laboratory conditions
Partition coefficient (log Kow): Not determined
Chemical stability: Stable under standard storage and handling conditions
Reactivity: No dangerous reactions expected under normal conditions
Possibility of hazardous reactions: Avoid mixing with strong oxidizing or reducing agents
Decomposition products: Heat or acids may release carbon oxides, nitrogen oxides, hydrogen bromide
Conditions to avoid: Excess moisture, high temperature, and exposure to light
Incompatible materials: Oxidizers, acids, strong bases
Likely routes of exposure: Inhalation, skin contact, eye contact, ingestion
Acute toxicity: Limited data; by analogy with other quaternary ammonium compounds, oral LD50 (mouse): >500 mg/kg
Skin corrosion/irritation: Causes local skin irritation in contact scenarios
Serious eye damage/irritation: Causes moderate to severe irritation
Respiratory effects: Inhalation of dust may cause respiratory tract discomfort
Carcinogenicity: No data available; not listed as carcinogen by NTP, IARC, OSHA
Reproductive toxicity: No chronic reproductive effects reported
Long-term effects: Prolonged or repeated exposure may cause dermatitis or mucous membrane irritation
Ecotoxicity: Toxic to aquatic organisms in large quantities due to bromide ion; data limited for this compound specifically
Persistence and degradability: Poorly biodegradable in soil and water environments
Bioaccumulative potential: Expected low due to low octanol-water partition coefficient
Mobility in soil: High solubility makes leaching possible in moist soil
Other adverse effects: Avoid uncontrolled release due to possible long-term aquatic impacts
Waste treatment methods: Chemical waste must be disposed of in accordance with federal, state, and local environmental control regulations
Packaging disposal: Contaminated containers should be emptied completely, rinsed, and disposed by licensed waste disposal contractor
Special precautions: Prevent uncontrolled entry into waterways, soil, or drains
Recommended disposal: Incineration in approved facility, or landfill in accordance with government guidelines
UN number: Not regulated as dangerous for most transport purposes
UN proper shipping name: Not classified as hazardous material
Transport hazard class: None assigned
Packing group: Not applicable
Environmental hazards: Not listed as marine pollutant
Special precautions: Protect from moisture and physical damage during transport. Label as laboratory chemical.
U.S. regulations: Not specifically regulated under SARA Title III Sections 302, 304, 311/312, or 313; not listed in California Proposition 65
International regulations: Not classified as a hazardous chemical in accordance with EU CLP Regulation (EC) No. 1272/2008
Inventory status: Listed on TSCA (US), EINECS (EU), DSL (Canada)
Workplace restrictions: Handle according to institutional chemical hygiene plans and OSHA Hazard Communication Standard
Other applicable regulations: Refer to specific national and regionally applicable guidelines for chemical handling, labeling, and safety data.
