Product Name: Triphenylphosphine
Chemical Formula: C18H15P
CAS Number: 603-35-0
EC Number: 210-036-0
Synonyms: Triphenylphosphan, PPh3
Manufacturer: Chemical suppliers, laboratory distributors
Recommended Uses: Used in laboratory synthesis, catalysis, organic chemistry research
GHS Classification: Acute toxicity (Oral, Category 4), Skin corrosion/irritation (Category 2), Serious eye damage/eye irritation (Category 2A), Hazardous to the aquatic environment-chronic (Category 2)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation, toxic to aquatic life with long lasting effects
Pictograms: Exclamation mark, Environment
Precautionary Statements: Avoid release to the environment, wash hands thoroughly after handling, wear protective gloves/eye protection/face protection, do not eat, drink or smoke when using product
Substance: Triphenylphosphine
Concentration: >98% (main component)
Molecular Weight: 262.29 g/mol
Other Components: No other hazardous ingredients present in significant concentration
Inhalation: Move the person to fresh air as quickly as possible, provide oxygen or artificial respiration if breathing is difficult, seek medical attention if symptoms like coughing or shortness of breath persist
Skin Contact: Remove contaminated clothing immediately, wash skin thoroughly with soap and water, monitor skin for rash or irritation, seek medical attention for persistent redness or pain
Eye Contact: Rinse eyes cautiously with plenty of water for at least fifteen minutes keeping eyelids apart, remove contact lenses if present and easy to do, seek prompt medical attention even if there are no immediate symptoms
Ingestion: Rinse mouth, do not induce vomiting unless instructed by a physician, seek medical assistance, never give fluids to an unconscious person
Suitable Extinguishing Media: Use dry chemical powder, carbon dioxide, or alcohol-resistant foam, water spray can be used for cooling containers, do not use water jet
Specific Hazards: Produces toxic and irritating fumes of phosphorus oxides during combustion, combustible but does not ignite readily
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear to prevent contact with skin and eyes, evacuate area if needed, prevent run-off from entering drains and water courses
Personal Precautions: Ensure adequate ventilation, keep unprotected persons away, avoid contact with eyes and skin, prevent inhalation of dust
Environmental Precautions: Prevent further leakage or spillage if safe to do so, do not let the product enter drains, surface or ground water
Methods for Cleaning Up: Collect spilled material with non-sparking tools and place in a tightly closed, suitable container for proper disposal, wash contaminated area with plenty of water, ventilate the area
Handling: Use proper personal protective equipment to avoid inhalation and direct skin contact, handle in a chemical fume hood when available, keep away from sources of ignition, do not ingest or inhale dust or fumes, follow good hygiene practices after handling the product
Storage: Store in tightly closed containers in a cool, dry and well-ventilated area, keep container away from heat, moisture and direct sunlight, store separately from oxidizing agents and strong acids, clearly label storage area and containers
Engineering Controls: Use local exhaust ventilation or process enclosure to minimize dust exposure, emergency eye wash fountains and safety showers should be available near the work area
Exposure Limits: No established OSHA PEL or ACGIH TLV for triphenylphosphine
Personal Protective Equipment: Respiratory protection such as a dust mask or respirator if airborne particles are generated, chemical-resistant gloves (nitrile or neoprene recommended), safety goggles or face shield, protective lab coat or coverall clothing, avoid wearing contact lenses
Appearance: White to off-white crystalline powder
Odor: Slight aromatic odor
Odor Threshold: Not available
pH: Not applicable (insoluble in water)
Melting Point: 79 - 81°C (174 - 178°F)
Boiling Point: 377°C (710°F) (decomposes)
Flash Point: 230°C (446°F)
Evaporation Rate: Not applicable
Flammability: Combustible solid
Vapor Pressure: Negligible at room temperature
Vapor Density: Not available
Relative Density: 1.19 g/cm3
Solubility: Insoluble in water, soluble in organic solvents such as benzene, toluene and ether
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not available
Decomposition Temperature: Above 377°C
Viscosity: Not applicable for powder
Chemical Stability: Stable under normal conditions of storage and handling, does not undergo hazardous polymerization
Possibility of Hazardous Reactions: May react with strong oxidizers and strong acids, can generate dangerous reactions with alkali metals
Conditions to Avoid: Exposure to heat, spark, flame, moisture, or strong oxidizing environments
Incompatible Materials: Strong acids, strong oxidizing agents, alkali metals
Hazardous Decomposition Products: Phosphorus oxides, carbon oxides, other toxic fumes on combustion or thermal decomposition
Acute Toxicity: Harmful if swallowed, inhaled or absorbed through skin, oral LD50 (rat): 700 mg/kg, no reliable data available for skin or inhalation LD50
Skin Corrosion/Irritation: Causes moderate skin irritation on contact
Serious Eye Damage/Irritation: Causes severe irritation and redness to eyes, risk of corneal injury
Respiratory Sensitization: May cause irritation of respiratory tract if inhaled, cough and throat discomfort occur in dusty environments
Germ Cell Mutagenicity: No data indicating mutagenic effects in humans or animals
Carcinogenicity: No classification as a carcinogen by IARC, NTP, OSHA or EU
Reproductive Toxicity: No data to suggest effect on fertility or fetal harm
Specific Target Organ Toxicity (Single Exposure): Data not available
Specific Target Organ Toxicity (Repeated Exposure): Prolonged exposure may cause liver or blood effects based on animal studies
Aspiration Hazard: Not classified as an aspiration hazard
Ecotoxicity: Toxic to aquatic organisms, may cause long-term adverse effects in aquatic environments, experimental data indicate acute LC50 for fish is between 1-10 mg/L
Persistence and Degradability: Persistant in the environment, low rate of chemical degradation in soil or water
Bioaccumulative Potential: Potential for bioaccumulation in aquatic species due to moderate log Kow value
Mobility in Soil: Low mobility, strong adsorption to soil particles, does not leach significantly
Other Adverse Effects: Avoid any product release into the environment and wastewater systems
Disposal Methods: Dispose in accordance with local, regional, national and international regulations, chemical waste generators must consult local authorities to determine proper disposal, incineration at a licensed facility recommended, avoid discharge into drains or waterways
Contaminated Packaging: Containers should be emptied and triple rinsed before disposal, dispose of packaging through hazardous waste collection services
Precautions: Handle surplus and waste material using personal protective equipment, keep waste in sealed containers
UN Number: Not classified as dangerous for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Avoid transport with food and feedstuffs, should not be allowed to enter the environment during transport
Special Precautions for User: Ensure containers are properly labeled, tightly sealed and secured during transport, avoid rough handling or exposure to moisture
TSCA: Listed on the United States Toxic Substances Control Act Inventory
EINECS/ELINCS: Listed in European Inventory of Existing Commercial Chemical Substances
REACH: Pre-registered in accordance with European Regulation (EC) No 1907/2006
SARA Title III: Not subject to reporting requirements under Sections 302, 304, 313
California Proposition 65: Not listed as a chemical known to the State of California to cause cancer or reproductive toxicity
Other International Regulations: Compliance with local and international regulations required for handling, storage, transport and disposal, safety data available from authorized bodies or suppliers
